Noggin is an indispensable factor in cartilage morphogenesis and joint formation, a potent inhibitor of bone morphogenetic protein (BMP) signaling, and plays a crucial role in the growth and patterning of the neural tube and somites.By forming homodimers, Noggin acts as a key regulator to inhibit chondrocyte differentiation by interacting with growth and differentiation factors, particularly GDF5 and possibly GDF6.Noggin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Noggin protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
90
Formula:
18121(Gene_ID)P97466 (Q28-C232)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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