EGFR is a transmembrane glycoprotein. EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. EGFR Protein, Human (621a.a, CHO, His) is a recombinant EGFR protein expressed by CHO, with a C-His tag and glycosylation modification[1][3][4][5].
Molecular Weight:
95-115 kDa
Purity:
96.80
Formula:
1956(Gene_ID)P00533-1 (L25-S645)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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