TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. It interacts with MMP2 through its C-terminal region, specifically targets the C-terminal PEX domain and inhibits MMP2 activity. TIMP-2 Protein, Human (HEK293) is the recombinant human-derived TIMP-2 protein, expressed by HEK293 , with tag free.
Molecular Weight:
Approximately 20 kDa, based on SDS-PAGE under reducing conditions.
Purity:
96.90
Formula:
7077(Gene_ID)P16035 (C27-P220)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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