TrkC Protein, a receptor tyrosine kinase, crucially contributes to nervous system and potential heart development. Upon NTF3/neurotrophin-3 binding, TrkC undergoes autophosphorylation, activating pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways regulate cell survival and differentiation, emphasizing TrkCs pivotal role in essential cellular processes during development. TrkC Protein, Human (HEK293, His-Fc) is the recombinant human-derived TrkC protein, expressed by HEK293 , with C-hFc, C-His labeled tag.
Molecular Weight:
Approximately 110-120 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
