PTP1B is an important tyrosine protein phosphatase that regulates the endoplasmic reticulum unfolded protein response by dephosphorylating EIF2AK3/PERK and inhibiting its kinase activity. It affects the signaling cascade induced by CKII and p60c-src, and may regulate the EFNA5-EPHA3 pathway, affecting cell reorganization. PTP1B Protein, Human (His) is the recombinant human-derived PTP1B protein, expressed by E. coli , with N-His labeled tag.
Molecular Weight:
Approximately 38 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
5770(Gene_ID)P18031 (E2-N321)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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