HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth and acts as a hepatotrophic factor for various tissues. As an activating ligand for MET receptor tyrosine kinase, HGF binds and promotes dimerization, activating MAPK signaling through TMPRSS13 cleavage. Structurally, HGF comprises alpha and beta chains connected by a disulfide bond. Interaction with SRPX2 enhances its mitogenic activity. HGF Protein, Mouse (HEK293) is the recombinant mouse-derived HGF protein, expressed by HEK293 , with tag free.
Molecular Weight:
Approximately 90-95 kDa & 60-62 kDa & 30-33 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
96.70
Formula:
15234(Gene_ID)Q08048-1 (Q33-L728)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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