HA/Hemagglutinin, Influenza B (ACO05957, HEK293, His) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P73943
Supplier Catalog Number:
HY-P73943
Alternative Catalog Number:
MCE-HY-P73943-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Alternative Names:
HA/Hemagglutinin Protein, Influenza B (ACO05957, HEK293, His),Virus,HEK293
Hemagglutinin (HA) is a class I viral fusion protein which is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. HA binds to sialic acid-containing receptors on the cell surface to bring about the attachment of the virus particle to the cell. The attachment of HA induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. HA plays a major role in the determination of host range restriction and virulence. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide and forming fusion pore. Several HA trimers are required to form a competent fusion pore[1][2]. HA/Hemagglutinin Protein, Influenza B (ACO05957, 556a.a, HEK293, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 80-90 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
/(Gene_ID)ACO05957 (D16-A556)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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