CD40L/CD154/TRAP, Rat (HEK293, Fc) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P74294
Supplier Catalog Number:
HY-P74294
Alternative Catalog Number:
MCE-HY-P74294-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Alternative Names:
CD40L/CD154/TRAP Protein, Rat (HEK293, Fc),Rat,HEK293
CD40L (CD154, TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-kappaB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in rat, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Rat (HEK293, Fc) has a total length of 146 amino acids (G115-L260), is expressed in HEK392 cells with N-terminal hFc-tag.
Molecular Weight:
Approximately 53 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
