CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through the TRAF6 and MAP3K8 pathways, activates ERK in macrophages and B cells, and induces immunoglobulin secretion.CD40 exists in monomeric and homodimeric forms, interacts with TRAF proteins (TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6) and crucially mediates cellular responses to external signals.CD40 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived CD40 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
