CD28 Protein activates T-cells, promoting cell proliferation, cytokine production, and T-cell survival. It collaborates with TCR/CD3 ligation and CD40L costimulation to boost IL4 and IL10 production in T-cells. CD28 Protein forms a disulfide-linked homodimer and interacts with DUSP14. It also binds to CD80/B7-1 and CD86/B7-2/B70, and interacts with GRB2 (By similarity). CD28 Protein, Rat (HEK293, His) is the recombinant rat-derived CD28 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
The protein migrates as approximately 30-36 kDa under reducing SDS-PAGE due to glycosylation.
Purity:
95.00
Formula:
25660(Gene_ID)P31042 (N20-K149)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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