The B7-H4 protein acts as a negative regulator and inhibits T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. Significant significance can be observed when expressed on tumor macrophages, cooperating with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 50-60 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
242122(Gene_ID)Q7TSP5 (F29-S256)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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