UBASH3B/STS1 protein blocks CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases, leading to the accumulation of activating receptors such as T cell receptors and EGFR on the cell surface. It exhibits tyrosine phosphatase activity against substrates such as EGFR, FAK, SYK and ZAP70. UBASH3B/STS1 Protein, Human (His) is the recombinant human-derived UBASH3B/STS1 protein, expressed by E. coli , with N-His labeled tag.
Molecular Weight:
Approximately 32-34 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95
Formula:
84959(Gene_ID)Q8TF42 (Q382-E649)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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