IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1alpha, IL-1beta, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-kappaB, MAPK pathways [1]. IL-1R1 Protein, Rat (HEK293, His) is a recombinant rat extracellular region of IL-1R1 (M1-K352) with a C terminal His tag, which is produced in HEK293 cells.
Molecular Weight:
52-75 kDa
Purity:
98
Formula:
25663(Gene_ID)NP_037255.3 (L34-K352)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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