IFN-alpha/beta R2, Human (Biotinylated, HEK293, His) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P74861
Supplier Catalog Number:
HY-P74861
Alternative Catalog Number:
MCE-HY-P74861-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Alternative Names:
IFN-alpha/beta R2 Protein, Human (Biotinylated, HEK293, His),Human,HEK293
IFN-alpha/beta R2, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFN-alpha/beta R2 forms the heterodimeric receptor with IFNAR1, and binds to type I IFNs[1]. IFN-alpha/beta R2 also interacts with JAK1 and leads to tyrosine phosphorylation of the IFNARs and STAT proteins[2]. Upon activation by these IFNs, IFNAR1 and IFN-alpha/beta R2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFN-alpha/beta R2 Protein, Human (Biotinylated, HEK293, His) is a recombinant biotinylated human IFN-alpha/beta R2 (I27-K243) with C-terminal His tag, which is produced in HEK293 cells.
Molecular Weight:
Approximately 43.04 kDa
Purity:
98
Formula:
3455(Gene_ID)P48551-1 (I27-K243)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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