EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Human (HEK293, His) is the recombinant human-derived EDAR protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
The protein migrates as an approximately 25-35 kDa band under reducing SDS-PAGE due to glycosylation.
Purity:
95.00
Formula:
10913(Gene_ID)Q9UNE0-1 (E27-I189)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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