The DR6/TNFRSF21 protein participates in multiple cellular processes and promotes apoptosis through NF-kappa-B activation, BAX-mediated pathways, and cytochrome c release. It is critical for neuronal apoptosis, particularly in response to APP-derived amyloid peptides, and is critical for normal cell body death and axonal pruning. DR6/TNFRSF21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DR6/TNFRSF21 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 55-80 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formula:
94185(Gene_ID)Q9EPU5 (Q42-H349)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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