DAP10 is a transmembrane adapter protein that forms the activating receptor KLRK1-HCST, which is critical for cytotoxicity in target cells expressing stress-inducing ligands. It is activated by ULBP, triggering calcium mobilization and activating PI3K, MAP2K/ERK and JAK2/STAT5 signaling pathways. DAP10 Protein, Human (HEK293, mFc) is the recombinant human-derived DAP10 protein, expressed by HEK293 , with C-mFc labeled tag.
Molecular Weight:
Approximately 33-45 kDa
Purity:
98
Formula:
10870(Gene_ID)Q9UBK5 (Q19-P48)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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