The CLEC1B/CLEC-2 protein serves as a platelet receptor for PDPN. When activated, it signals through SRC and SYK kinases, activating PLCG2. CLEC1B forms homodimers and interacts with RACK1, promoting its ubiquitination and degradation. It also interacts with SYK and PDPN, independently of glycosylation, activating CLEC1B/CLEC-2. CLEC1B/CLEC-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC1B/CLEC-2 protein, expressed by HEK293 , with N-hFc labeled tag.
Molecular Weight:
Approximately 50-65 kDa due to the glycosylation.
Purity:
98
Formula:
56760(Gene_ID)Q9JL99-1 (M53-L229)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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