PDE3A Protein, Human (sf9, His-GST),Human,Sf9 insect cells
PDE3A protein, a cyclic nucleotide phosphodiesterase, targets cAMP, cGMP, and cUMP, crucial in diverse physiological processes. In an E2/17beta-estradiol-induced pro-apoptotic pathway, E2 stabilizes the PDE3A/SLFN12 complex, leading to SLFN12 dephosphorylation and activating its pro-apoptotic ribonuclease activity. This pathway is implicated in tissues with high E2 concentrations, potentially contributing to processes like placenta remodeling. PDE3A Protein, Human (sf9, His-GST) is the recombinant human-derived PDE3A protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
Molecular Weight:
Approximately 93 kDa
Purity:
90.00
Formula:
5139(Gene_ID)Q14432 (K669-Q1141)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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