RSPO2 is a key activator of the canonical Wnt pathway and acts as a ligand for LGR4-6 receptors (LGR4, LGR5, or LGR6). Upon binding, this complex forms with phosphorylated LRP6 and Frizzled receptors, activating the canonical Wnt pathway and upregulating target genes. RSPO2/R-spondin-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived RSPO2/R-spondin-2 protein, expressed by HEK293 , with C-mFc labeled tag.
Molecular Weight:
Approximately 45-50 kDa, based on SDS-PAGE under reducing conditions.
Purity:
92.00
Formula:
239405(Gene_ID)Q8BFU0 (N24-G205)(Accession)
Application Notes:
Recombinant Proteins
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