TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-alpha). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Mouse (HEK293, Fc) is expressed by HEK293 and has a transmembrane region with Fc tag at the C-terminus[1].
Molecular Weight:
Approximately 65 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
21938(Gene_ID)P25119 (M1-G258)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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