VHL protein is an important component of the von Hippel-Lindau ubiquitination complex and plays a key role in ubiquitination and proteasomal degradation. As a target recruitment subunit in the E3 ubiquitin ligase complex, VHL specifically recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions and regulates cellular responses to oxygen levels. VHL Protein, Human (His) is the recombinant human-derived VHL protein, expressed by E. coli , with N-6*His labeled tag.
Molecular Weight:
Approximately 34 kDa, based on SDS-PAGE under reducing conditions.
Purity:
90.00
Formula:
7428(Gene_ID)P40337 (M1-D213)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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