FOLR2 Protein binds folate, enabling the transport of 5-methyltetrahydrofolate into cells with high affinity under neutral pH. Upon endocytosis, exposure to slightly acidic pH induces a conformational change, substantially reducing FOLR2s folate affinity and releasing it from the receptor. FOLR2 Protein, Human (HEK293, His) is the recombinant human-derived FOLR2 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 28-35 kDa due to the glycosylation.
Purity:
97
Formula:
2350(Gene_ID)P14207 (T17-H228)(Accession)
Application Notes:
Recombinant Proteins
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