UBASH3A interferes with CBL-mediated downregulation and degradation of receptor-type tyrosine kinases and promotes the accumulation of activating receptors such as T cell receptors, EGFR and PDGFRB on the cell surface. It exhibits minimal protein tyrosine phosphatase activity and may act as a dominant negative regulator of UBASH3B-dependent dephosphorylation. UBASH3A Protein, Human (His) is the recombinant human-derived UBASH3A protein, expressed by E. coli , with N-His labeled tag.
Molecular Weight:
Approximately 30 kDa
Purity:
98
Formula:
53347(Gene_ID)P57075-2 (A354-N623)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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