GABARAP Protein is essential for regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) involved in RAC1 activation and downstream signaling. The D6/7 E3 ubiquitin ligase complex, where GABARAP is a key component, contributes to diverse biological processes, including cytoskeletal organization, cell migration, proliferation, and apoptosis. GABARAP Protein, Human (His-MBP) is the recombinant human-derived GABARAP protein, expressed by E. coli , with N-His, N-MBP labeled tag.
Molecular Weight:
Approximately 49-58 kDa,based on SDS-PAGE under reducing conditions.
Formula:
11337(Gene_ID)O95166 (M1-L117)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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