GPR114, an adhesion G protein-coupled receptor (GPCR), crucially activates the adenylate cyclase pathway by coupling with G(s) subunit alpha. Isoform 1, displaying constitutive activity, elevates basal cyclic AMP (cAMP) levels and responds to mechanical stimulation, emphasizing GPR114s functional significance in intracellular signaling cascades and its role in cellular responses to mechanical cues. GPR114 Protein, Human (HEK293, Fc) is the recombinant human-derived GPR114 protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 57-75 kDa due to the glycosylation.
Purity:
95
Formula:
221188(Gene_ID)Q8IZF4 (E22-G184)(Accession)
Application Notes:
Recombinant Proteins
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