IFN-lambda 2/IL-28A, Human (P.pastoris, His) Preis auf Anfrage

Catalog Number: MCE-HY-P77005
Article Name: IFN-lambda 2/IL-28A, Human (P.pastoris, His) Preis auf Anfrage
Biozol Catalog Number: MCE-HY-P77005
Supplier Catalog Number: HY-P77005
Alternative Catalog Number: MCE-HY-P77005-1UNIT
Manufacturer: MedchemExpress
Category: Proteine/Peptide
Alternative Names: IFN-lambda 2/IL-28A Protein, Human (P.pastoris, His),Human,P. pastoris
IFN-lambda 2 (IL-28A) is a member of the Type-III interferon family. IFN-lambda 2 has antiviral antitumour and immunomodulatory activities[1]. IFN-lambda 2 signals through a heterodimeric receptor complex comprising IFNLR1 and IL-10RB. When binding to the receptor complex, Jak1 and Tyk2 will be activated, and leads to tyrosine phosphorylation of the IFN-lambdaR1 and activation of STAT1 and STAT2. Activated STAT1 and STAT2 together with IRF-9 form a trimeric transcription factor complex (ISGF3). The formed ISGF3 then translocate to the nucleus and promotes the production of IFN-stimulated genes (ISGs)[2]. IFN-lambda 2/IL-28A Protein, Human (P.pastoris, His) is a recombinant human IFN-lambda 2 (V26-V200) with C-terminal His tag, which is expressed in P.pastoris.
Molecular Weight: Approximately 21.1 kDa.
Formula: 282616(Gene_ID)Q8IZJ0 (V26-V200)(Accession)
Application Notes: MCE Product type: Recombinant Proteins