PTK9, an actin-binding protein, regulates motility and morphological processes by inhibiting actin polymerization and capping the barbed ends of filaments. It plays a crucial role in clathrin-mediated endocytosis and the distribution of endocytic organelles. PTK9 interacts with G-actin, capping protein (CP), and possibly TWF2 and phosphoinositides, particularly PI(4,5)P2, which down-regulates its activity. Additionally, it interacts with ACTG1. PTK9 Protein, Human (His-GST) is the recombinant human-derived PTK9 protein, expressed by E. coli , with N-His, N-GST labeled tag.
Molecular Weight:
Approximately 50 kDa, based on SDS-PAGE under reducing conditions.
Formula:
5756(Gene_ID)Q12792-4 (M1-D252)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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