The REG4 protein is a calcium-dependent lectin that functions as a pattern recognition receptor (PRR) in the innate immune system. REG4 has specific affinity for alpha-mannan on Candida albicans hyphae and triggers phosphorylation of the FCER1G immunoreceptor tyrosine activation motif (ITAM), thereby activating SYK, CARD9 and NF-kappa-B. REG4 Protein, Rat (HEK293, His) is the recombinant rat-derived REG4 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 20-31 kDa due to the glycosylation.
Purity:
95.00
Formula:
445583(Gene_ID)Q68AX7 (D23-P157)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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