CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching[1]. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system[2]. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division[3]. As for CD30 ligand in cynomolgus contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30 Ligand/TNFSF8 Protein, Cynomolgus (HEK293, hFc) is expressed in the HEK293 cells with a N-terminal hFc-tag.
Molecular Weight:
Approximately 59 kDa,based on SDS-PAGE under reducing conditions.
Formula:
/(Gene_ID)G7P2F1 (Q63-D234)(Accession)
Application Notes:
Recombinant Proteins
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