The IGFBP-3R protein was identified as an IGFBP3-specific cell death receptor and becomes a potential mediator of caspase-8-dependent apoptosis upon ligand binding. This receptor actively interacts with IGFBP3, forming a key molecular connection that may initiate the apoptotic signaling cascade. TMEM219/IGFBP-3R Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-3R protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 60-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95
Formula:
68742(Gene_ID)Q9D123-1 (G39-R204)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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