IL-18R alpha Protein, Human (HEK293, His-Avi),Human,HEK293
IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor alpha (Ralpha) and beta (Rbeta) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kbeta- inducing kinase, with subsequent activation of nuclear factor kbeta[2]. IL-18R alpha inhibits the production of IFN-gamma stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Human (HEK293, His-Avi) is a recombinant protein with a His-Avi label that consists of 311 amino acids (A19-R329) and is produced by HEK293 cells.
Molecular Weight:
60-70 kDa
Purity:
95
Formula:
8809(Gene_ID)Q13478 (A19-R329)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
* VAT and and shipping costs not included. Errors and price changes excepted
