MCEMP1, a type II transmembrane protein, is a lung-specific surface protein and functions as an adaptor for KIT, which promotes SCF-mediated mast cell proliferation. MCEMP1 elicits intracellular signaling through its cytoplasmic immunoreceptor tyrosine-based activation motif and forms a complex with KIT to enhance its autophosphorylation and activation. MCEMP1 regulates cell chemotaxis, adhesion, and migration in a TGFbeta dependent manner. MCEMP1 acts as a critical factor in allergic and inflammatory lung diseases[1][2]. MCEMP1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived MCEMP1 protein, expressed by HEK293 , with N-hFc labeled tag.
Molecular Weight:
Approximately 40-50 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
69189(Gene_ID)Q9D8U6 (K92-T183)(Accession)
Application Notes:
Recombinant Proteins
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