AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (HEK293, His-Avi) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Molecular Weight:
Approximately 70-80 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
558(Gene_ID)P30530-1 (A26-P449)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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