DNAM-1 protein is a key player in cell-cell adhesion and lymphocyte signaling, mediating cytotoxicity and lymphokine secretion of CTL and NK cells. As a receptor for NECTIN2, DNAM-1 stimulates T cell proliferation and cytokine production (IL2, IL5, IL10, IL13, and IFNG) upon ligand binding. DNAM-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DNAM-1 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 48-68 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
