KLRG1 Protein plays a pivotal role in inhibiting NK cells and T-cell functions by binding to non-MHC ligands. It engages in missing self-recognition, monitoring the expression of classical cadherins like E-cadherin/CDH1. Existing as a monomer or homodimer, KLRG1 employs its ITIM to interact with PTPN11 and INPP5D, modulating cellular responses and contributing to immune regulation. KLRG1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived KLRG1 protein, expressed by HEK293 , with N-hFc labeled tag.
Molecular Weight:
Approximately 50-65 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
50928(Gene_ID)O88713 (Q57-Y188)(Accession)
Application Notes:
Recombinant Proteins
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