RSPO1 activates the canonical Wnt signaling pathway by binding to the LGR4-6 receptor, triggering an increase in target gene expression. It inhibits ZNRF3, regulates the Wnt signaling pathway, and negatively regulates the TGF-beta pathway. RSPO1/R-spondin-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived RSPO1/R-spondin-1 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 40-50 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95.00
Formula:
192199(Gene_ID)Q9Z132 (S21-Q265)(Accession)
Application Notes:
Recombinant Proteins
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