CD40L/CD154/TRAP Trimer, Human (HEK293, His-Flag)

Product Overview

• Article Name: CD40L/CD154/TRAP Trimer, Human (HEK293, His-Flag)
• Biozol Catalog Number: MCE-HY-P78425
• Supplier Catalog Number: HY-P78425
• Alternative Catalog Number: MCE-HY-P78425-50UG, MCE-HY-P78425-20UG, MCE-HY-P78425-100UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag),Human,HEK293

Product Description

CD40L (CD154, TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-kappaB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag) is composed of a full-length monomer of 149 amino acids (M113-L261), is expressed in HEK392 cells with N-terminal His- and Flag-tag.

Product Properties

• Molecular Weight: Approximately 55 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
• Purity: 95
• Formula: 959(Gene_ID)P29965 (M113-L261)(Accession)

Application Notes

• Application Notes: Recombinant Proteins