TRAIL/TNFSF10 Trimer, Human (HEK293, His-Flag)

Product Overview

• Article Name: TRAIL/TNFSF10 Trimer, Human (HEK293, His-Flag)
• Biozol Catalog Number: MCE-HY-P78528
• Supplier Catalog Number: HY-P78528
• Alternative Catalog Number: MCE-HY-P78528-50UG,MCE-HY-P78528-20UG,MCE-HY-P78528-100UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: TRAIL/TNFSF10 Trimer Protein, Human (HEK293, His-Flag),Human,HEK293

Product Description

TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways[1][2]. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell[1]. TRAIL/TNFSF10 Protein, Human (HEK293, His-Flag) is a recombinant human TRAIL (G118-G281) with N-terminal His and Flag tag, which is expressed in HEK293.

Product Properties

• Molecular Weight: Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 95.00
• Formula: 8743(Gene_ID)P50591 (G118-G281)(Accession)

Application Notes

• Application Notes: Recombinant Proteins