GITR is a type I transmembrane protein. GITR mediates signal transduction through NF-kB and MAPK pathways. Protects T cells from cell death induced by TCR activation. GITR inhibits proliferation and induces apoptosis of Multiple Myeloma (MM) cells in vitro and in vivo. GITR Protein, Canine (HEK293, His) is the recombinant canine-derived GITR protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 19-25 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95
Formula:
606971(Gene_ID)D7F619 (G23-P154)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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