Klotho beta protein represses cholesterol 7-alpha-hydroxylase (CYP7A1), a key enzyme in bile acid synthesis. It enhances binding between fibroblast growth factor receptors and fibroblast growth factor 21, and directly interacts with FGF19 and FGF21. This positions Klotho beta as a crucial modulator of metabolic and growth factor signaling pathways. Klotho beta Protein, Mouse (HEK293, His) is the recombinant mouse-derived Klotho beta protein, expressed by HEK293 , with C-10*His labeled tag.
Molecular Weight:
Approximately 125-130 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95.00
Formula:
83379(Gene_ID)Q99N32 (F53-L995)(Accession)
Application Notes:
Recombinant Proteins
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