The ADAM17/TACE protein cleaves TNF-alpha, releasing it from the membrane and activating various cell surface proteins such as JAM3, ACE2, and the p75 TNF receptor. It also triggers the Notch pathway by cleaving Notch into membrane-associated fragments. ADAM17/TACE Protein, Mouse (HEK293, His) is the recombinant mouse-derived ADAM17/TACE protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 55-75 & 25 kDa due to the glycosylation.
Purity:
95.00
Formula:
11491(Gene_ID)Q9Z0F8 (P18-D563)(Accession)
Application Notes:
Recombinant Proteins
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