ZNRF3, as an E3 ubiquitin protein ligase, plays a crucial role as a negative regulator in the Wnt signaling pathway. It does this by mediating the ubiquitination and subsequent degradation of components within the Wnt receptor complex, namely Frizzled and LRP6. ZNRF3 Protein, Human (HEK293, His) is the recombinant human-derived ZNRF3 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 22-25 kDa, based on SDS-PAGE under reducing conditions.
Purity:
96
Formula:
84133(Gene_ID)Q9ULT6-1 (K56-M219)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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