Norrin protein is a key component of the canonical Wnt signaling pathway, activating the cascade by interacting with the FZD4 receptor and LRP5 coreceptor. Its role in retinal vascularization includes serving as a FZD4 ligand, stabilizing beta-catenin (CTNNB1), and initiating LEF/TCF-mediated transcription. Norrin Protein, Mouse is the recombinant mouse-derived Norrin protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 13 kDa
Purity:
97.00
Formula:
17986(Gene_ID)P48744 (K25-S131)(Accession)
Application Notes:
Recombinant Proteins
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