Batoclimab (RVT-1401) is a fully humanized IgG1 monoclonal antibody targeting FcRn. Batoclimab has high affinity for the IgG-binding site on FcRn. By competitively binding to the IgG binding site on FcRn, Batoclimab blocks FcRn-mediated recycling of IgG, resulting in enhanced degradation and subsequent reductions in IgG levels. Batoclimab can be used in the research of autoimmune diseases such as myasthenia gravis and thyroid eye disease[1][2].
Molecular Weight:
(143.43 kDa)
Purity:
99.89
CAS Number:
[2187430-05-1]
Target:
Fc Receptor (FcR)
Application Notes:
MCE Product type: Inhibitory Antibodies
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