Anti-Mouse LPAM-1/Integrin alpha4beta7 Antibody (DATK32) is a rat-derived anti-LPAM-1/Integrin alpha4beta7 IgG2a, kappa type antibody inhibitor. Anti-Mouse LPAM-1/Integrin alpha4beta7 Antibody (DATK32) specifically reacts with both chains of the alpha4beta7 heterodimer and blocks the adhesion to immobilized mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Anti-Mouse LPAM-1/Integrin alpha4beta7 Antibody (DATK32) suppresses the proliferation and cytokine secretion of CD8+ T cells. Anti-Mouse LPAM-1/Integrin alpha4beta7 Antibody (DATK32) decreases Peyers patches and follicular B cells in mice. Anti-Mouse LPAM-1/Integrin alpha4beta7 Antibody (DATK32) can be used for the researches of inflammation, such as ulcerative colitis[1][2][3][4].
Molecular Weight:
(150 kDa)
Purity:
97
Target:
Integrin
Application Notes:
MCE Product type: Inhibitory Antibodies
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