Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer[1][2][3][4].
Molecular Weight:
(145.52 kDa)
Purity:
99.9
CAS Number:
[1796566-95-4]
Target:
ADC Antibody,TROP2
Application Notes:
MCE Product type: Inhibitory Antibodies
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