Tanruprubart (ANX005) is a C1q inhibitor and C1q depleter. Tanruprubart is a human antibody expressed in CHO cells, with huIgG1 heavy chains and hukappa light chains, and its predicted molecular weight (MW) is 145 kDa. For the isotype control of Tanruprubart, refer to Human IgG1 kappa, Isotype Control (HY-P99001). The IC50 of Tanruprubart is 346 ng/mL for humans and 259 ng/mL for rats, its EC50 is 3.8 ng/mL for humans, 5.2 ng/mL for rats, and 9.9 ng/mL for mice. Tanruprubart is applicable to the research of Guillain-Barre syndrome and Alzheimers disease[1].
Molecular Weight:
(145.78 kDa)
Purity:
99.86
CAS Number:
[2065212-40-8]
Target:
Complement System
Application Notes:
MCE Product type: Inhibitory Antibodies
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