Aplitabart (IGM-8444) is a a pentameric IgM DR5 agonist antibody with 10 binding sites specific for DR5. Aplitabart multimerizes DR5 to selectively and potently induce tumor cell apoptosis. Aplitabart can be used for the study of lung cancer, breast cancer, cute myeloid leukemia (AML) and low-grade B-cell non-Hodgkin lymphoma (B-NHL)[1].
Molecular Weight:
(871.57 kDa)
Purity:
97.024
CAS Number:
[2796349-94-3]
Target:
Apoptosis,TNF Receptor
Application Notes:
MCE Product type: Inhibitory Antibodies
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