Zaltenibart (OMS906) is an IgG4 humanized monoclonal antibody and MASP-3 inhibitor. By inhibiting MASP-3, Zaltenibart achieves upstream inhibition of the alternative complement pathway. MASP-3 is an upstream activator of Factor D (Factor D), a key enzyme in the alternative complement pathway. Zaltenibart prevents both intravascular hemolysis and extravascular hemolysis. Zaltenibart is applicable to research related to paroxysmal nocturnal hemoglobinuria[1][2].
Molecular Weight:
(144.437 kDa)
Purity:
99
CAS Number:
[2527079-60-1]
Target:
Complement System,Ser/Thr Protease
Application Notes:
MCE Product type: Inhibitory Antibodies
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